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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIPE
All Species:
9.39
Human Site:
S616
Identified Species:
29.52
UniProt:
Q05469
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05469
NP_005348.2
1076
116598
S616
D
L
R
E
G
Q
D
S
E
E
L
S
S
L
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533655
889
96890
S455
D
L
R
E
G
Q
D
S
E
E
L
S
S
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P54310
759
83329
E325
L
N
S
L
A
K
S
E
G
P
R
L
E
L
R
Rat
Rattus norvegicus
P15304
1068
116793
S615
D
L
R
E
G
Q
D
S
K
M
L
N
S
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001124413
832
91875
Y398
R
A
L
E
E
C
F
Y
A
Y
C
W
A
L
K
Zebra Danio
Brachydanio rerio
XP_686139
538
59103
F104
S
S
N
R
R
S
I
F
F
R
A
S
H
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397143
733
81786
N299
E
L
T
L
S
T
L
N
G
S
T
I
S
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194738
827
91195
W393
H
E
I
Y
L
R
S
W
A
K
D
L
G
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
66.6
N.A.
60.3
71.9
N.A.
N.A.
N.A.
44.3
33.7
N.A.
N.A.
26
N.A.
32.1
Protein Similarity:
100
N.A.
N.A.
72.6
N.A.
64.5
79.6
N.A.
N.A.
N.A.
55.1
43
N.A.
N.A.
40.7
N.A.
46.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
6.6
73.3
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
13.3
86.6
N.A.
N.A.
N.A.
20
6.6
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
13
0
0
0
25
0
13
0
13
0
25
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% C
% Asp:
38
0
0
0
0
0
38
0
0
0
13
0
0
0
0
% D
% Glu:
13
13
0
50
13
0
0
13
25
25
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
13
13
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
38
0
0
0
25
0
0
0
13
0
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
13
0
0
0
13
0
0
0
0
13
0
13
13
% I
% Lys:
0
0
0
0
0
13
0
0
13
13
0
0
0
0
13
% K
% Leu:
13
50
13
25
13
0
13
0
0
0
38
25
0
63
0
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
13
13
0
0
0
0
13
0
0
0
13
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
25
% P
% Gln:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
38
13
13
13
0
0
0
13
13
0
0
0
13
% R
% Ser:
13
13
13
0
13
13
25
38
0
13
0
38
50
0
0
% S
% Thr:
0
0
13
0
0
13
0
0
0
0
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
13
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
13
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _